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Saeb-Parsy Lab

Department of Surgery
 

The Saeb-Parsy lab research programmed is underpinned by a commitment to develop and support a broad multidisciplinary collaborative network. A list of our active collaborators and projects is give below, and further details on collaborations are provided in the Research Themes and Networks and Links sections of the website.

Collaborator List

Andrew Lever - Department of Medicine, University of Cambridge 

  • Use of endothelial cells for amelioration of kidney ischaemia-reperfusion injury

Athina Markaki - Department of Engineering, University of Cambridge

  • Generation of bioengineered bile ducts

Catherine Betts - AstraZeneca

  • Use of humanised mice for testing efficacy and safety of Tregs

Cedric Ghevaert - Cambridge Stem Cell Institute

  • Immunogenicity of iPSC-derived megakaryiocytes and platelets

Chris Watson - Department of Surgery, University of Cambridge

  • Trafficking of cholangiocyte organoids in ex vivo perfused human livers

Christian Frezza - MRC Cancer Unit, University of Cambridge

  • Metabolomics signature of ischaemia and reperfusion injury

Elisa Laurenti - Cambridge Stem Cell Institute

  • Characterisation of haemtopoietic stem cells

Fotis Sampaziotis - Laboratory of Regenerative Medicine, University of Cambridge

  • Generation and characterisation of primary and iPSC-derived cholangiocyte organoids

Francesco Colucci - Department of Obstetrics and Gynaecology, University of Cambridge

  • The NK T cell response to iPSC-derived beta-like cells

Francesco Pampaloni - Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt

  • High throughout image analysis of pancreatic organoids

Frank Waldron-Lynch - Department of Medicine, University of Cambridge

  • Autoimmune response to iPSC-derived beta-like cells

Geoff Woods - Cambridge Institute for Medical Research

  • Characterisation of human dorsal root ganglia

Giovanna Lombardi - Immunomodulation Laboratory, King's College London

  • Tregs and CAR T cells for modulation of immune response to iPSC-derived beta-like cells

Grant Stewart - Department of Surgery, University of Cambridge

  • mtDNA and ischaemia-reperfusion injury during partial nephrectomies for renal cell carcinoma

Gregory TietjenDepartment of Biomedical Engineering, Yale University

  • Developing nanoparticles for delivery of targeted drugs  

Hamid Sabourian - Faculty of Economics, University of Cambridge

  • Application of Game theory to decision making in transplantation

Inigo Martincorena - Wellcome Trust Sanger Institute, Cambridge

  • Mutation burden in pancreas, bladder and other tissues

Jo Jones - Department of Neurosciences, University of Cambridge

  • Tissue-resident T cells

John Casey - The Scottish Islet Laboratory, University of Edinburgh

  • Use of pancreatic islets

John Todd - Nuffield Department of Medicine, University of Oxford

  • Pathogenesis of type 1 diabetes mellitus

Kaivan MunshiFaculty of Economics, University of Cambridge

  • Application of Game theory to decision making in transplantation

Kathleen Liddell - Faculty of Law, University of Cambridge

  • Legal regulation of transplantation

Ljijana Fruk - Department of Chemistry, University of Cambridge

  • Use of nanoparticles to study pancreatic islet cryopreservation

Lorna Marson - Department of Surgery, University of Edinburgh

  • Ischaemia-reperfusion in clinical kidney transplantation

Ludovic Vallier - Laboratory for Regenerative Medicine, University of Cambridge

  • Function and immunogenicity of regenerative cellular therapies

Magdalena Zernicka-Goetz - Department of Physiology, Development and Neurobiology, University of Cambridge

  • In vivo assessment of cultured blastocysts

Matthew Dyson - Faculty of Law, University of Oxford

  • Legal regulation of transplantation

Menna Clatworthy - Department of Medicine, University of Cambridge

  • Phenotyping of tissue resident B cells

Meritxell Huch - Gurdon Institute, University of Cambridge

  • Development of pancreatic organoids for treatment of type 1 diabetes

Mike Allison - Department of Medicine, University of Cambridge

  • Humoral rejection in liver transplantation

Mike Murphy - Mitochondrial Biology Unit, University of Cambridge

  • Mitochondrial mechanisms and therapeutic approaches in ischaemia-reperfusion injury

Mike Nicholson - Department of Surgery, University of Cambridge

  • Use of ex vivo normothermic perfusion to assess ischaemia-reperfusion injury

Mike Stratton - The Wellcome Trust Sanger Institute, University of Cambridge 

  • DNA mutations in embryogenesis

Mike StubbingtonThe Wellcome Trust Sanger Institute, University of Cambridge 

  • Transcriptomic profiling of healthy live tissues

Nigel Slater - Department of Chemical Engineering and Biotechnology, University of Cambridge

  • Cryopreservation of multicellular aggregates and bioengineered tissues

Peter CampbellThe Wellcome Trust Sanger Institute, University of Cambridge

  • Burden of mutation in colon, bone marrow and prostate

Phil JonesThe Wellcome Trust Sanger Institute, University of Cambridge

  • Burden of mutation in oesophagus

Raaj Praseedom - Department of Surgery, Cambridge University Hospitals NHS Trust

  • Development of tumoroids models of hepatopancreaticobiliary cancer

Rebecca Brais - Department of Histopathology, Cambridge University Hospitals NHS Trust

  • Histopathological assessment of pancreases to determine suitability for transplantation

Rebecca Fitzgerald - MRC Cancer Unit, Cambridge

  • Transcriptomic analysis of oesophageal epithelium

Richard Hartley - WestCHEM School of Chemistry, University of Glasgow

  • Mitochondria-targeted therapies to reduce ischaemia-reperfusion injury

Richard Stebbings - MedImmune

  • Investigation of safety of cancer immunotherapies using humanised mice

Sarah Bohndiek - Department of Physics

  • Application of Raman Spectroscopy for investigation of intracellular cryoprotectant concentrations 

Sarah Hosgood - Department of Surgery, University of Cambridge

  • Ex vivo normothermic perfusion of isolated organs to investigate ischaemia-reperfusion injury 

Sarah TeichmannThe Wellcome Trust Sanger Institute, University of Cambridge 

  • Transcriptomic studies using normal human tissues 

Sathia Thiru - Department of Pathology, University of Cambridge

  • Histopathological assessment of kidney ischaemia-reperfusion injury 

Silvia Guinoud - AstraZaneca

  • Histopathological characterisation of humanised mouse models

Sonje Reiche - Faculty of Economics, University of Cambridge

  • Application of Economic Game Theory to decision making in transplantation

Tamir Rashid - Centre for Stem Cells & Regenerative Medicine, King's College London

  • In vivo assessment of iPSC-derived hepatocytes

Thomas Krieg - Department of Medicine, University of Cambridge

  • Mitochondrial mechanisms and therapeutic targets in ischaemia-reperfusion injury

Will Gelson - Department of Hepatology, Cambridge University Hospitals NHS Trust

  • Antibody-mediated rejection in liver transplantation