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Saeb-Parsy Lab

Department of Surgery

Studying at Cambridge

 

Research Themes

To learn about experimental and clinical research by the Saeb-Parsy Group please follow links below.
Experimental Research

Our experimental research programme is focused on transplantation of cells, bioengineered tissues, organs and tumours in three main themes. Our overall aim is to study the function and immunogenicity of fresh and cryopreserved transplanted cells and tissues, to ameliorate the immune response and ischaemia-reperfusion injury after transplantation, and to study safety and efficacy of cancer immunotherapies. Our programme makes extensive use of immunodeficient and immune-reconstituted humanised mice and mouse, pig and human models of ischaemia-reperfusion injury.

Clinical Reserach

Our clinical research programme is focused on outcomes after kidney, pancreas and liver transplantation through or leadership or participation in randomised clinical trials, cohort studies and retrospective reviews of local and national data. We have also engaged in multidisciplinary collaborations with colleagues from the facilities of law and economics to study non-clinical aspects of transplantation.