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Clinical Transplantation Outcomes

Clinical Transplantation Outcomes

Our clinical research programme is focused on outcomes after kidney, pancreas and liver transplantation. Kourosh Saeb-Parsy is the chief investigator in a randomised clinical trial (RCT) on the timing of stent removal after kidney transplantation and aa co-investigator in two RCTs studying the potential of heme arginate an ex vivo normothermic perfusion to improve outcomes after kidney transplantation. Our group is also focused on prospective cohort studies and retrospective data analysis to identify factors that predict outcomes after transplantation, with an emphasis on early graft loss.

Selected Related Publications:

  • Hakeem A, Chen J, Iype S, Clatworthy M, Watson C, Godfrey EM, Upponi S, Saeb-Parsy K (2017) Pancreatic Allograft Thrombosis: Suggestion for a CT grading system and management algorithm. American Journal of Transplantation (in press).
  • Barlow AD, Saeb-Parsy K, Watson CJ (2017) An analysis of the survival outcomes of simultaneous pancreas and kidney transplantation compared to live donor kidney transplantation in patients with type 1 diabetes: a UK Transplant Registry study. Transplant International (in press).
  • Hosgood SA, Saeb-Parsy K, Wilson C, Callaghan C, Collett D, Nicholson ML (2017) Protocol of a randomised controlled, open-label trial of ex vivo normothermic perfusion versus static cold storage in donation after circulatory death renal transplantation. BMJ Open Jan 23;7(1):e012237.
  • Hosgood SA, Saeb-Parsy K, Hamed MO, Nicholson ML (2016) Successful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion. American Journal of Transplantation 16:3282-3285.
  • Hamed MO, Chen Y, Pasea L, Watson CJ, Torpey N, Bradley JA, Pettigrew GJ, Saeb-Parsy K (2015) Early graft loss after kidney transplantation: risk factors and consequences. American Journal of Transplantation 15:1632-43.
  • Dare A, Pettigrew GJ, Saeb-Parsy K (2014) Pre-operative assessment of the deceased donor kidney: from macroscopic appearance to molecular biomarkers. Transplantation 97:797-807.